Published : 29 September 2025

Mythbusting The Effect of BCAA on Wound Healing

  • Ferdian Tanaka
  • Shaza Nathasya Sandakh
  • Geovan Hananto
  • Antonius Setiadi

Volume 12, Issue 2, Jurnal Plastik Rekonstruksi | Pages : 62-69

DOI: 10.14228/jprjournal.v12i2.24   Reader : 75 times PDF Download : 23 times

Abstract

Nutrition plays a crucial role in the wound-healing process. Nutrition deficiencies can hinder the wound healing process and prolong the recovery period turning the wound into a chronic wound. One nutrient that is rarely discussed is BCAA (Branched Chain Amino Acid). BCAA are essential amino acids that are believed to accelerate the wound healing process. This study aims to investigate the effects of BCAA on the wound healing process. Studies have shown that BCAAs can increase serum albumin levels by preventing the formation of mRNA-PTB (Polypyrimidine Tract-Binding Protein) in liver cells, which activates and accelerates the wound healing process. Administering BCAA as a single treatment is not optimal; therefore, combined therapy with other essential amino acids is necessary. BCAAs can be administered orally, enterally, parenterally, and topically.

Data Availability

All data generated during this study are included in this published article [and its supplementary information files].

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Keywords

  • Nutrition
  • BCAA
  • Wound Healing
  • Protein
  • Amino acid

Author Information

Ferdian Tanaka

Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.

Email: ferdiantanaka@gmail.com

ORCID : https://orcid.org/0009-0003-3883-0480

Shaza Nathasya Sandakh

Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.

Email: shazasandakh@gmail.com

ORCID : https://orcid.org/0009-0004-5089-4070

Geovan Hananto

Brawijaya University , Indonesia.

Email: geovan.hananto@gmail.com

ORCID : https://orcid.org/0009-0005-6156-8868

Antonius Setiadi

Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.

Email: antonius.setiadi69@gmail.com

ORCID : https://orcid.org/0009-0009-4300-4822

Article History

Submitted : 4 February 2025
Revised : 10 June 2025
Published : 29 September 2025

How to Cite This

Tanaka, F., Sandakh, S. N., Hananto, G., & Setiadi, A. (2025). Mythbusting The Effect of BCAA on Wound Healing. Jurnal Plastik Rekonstruksi, 12(2), 62–69. https://doi.org/10.14228/jprjournal.v12i2.24

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